List of Ongoing Clinical Trial - Taipei Medical University Hospital
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Symptom
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IRB NO.
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Clinical trial title
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Principal Investigator
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Department
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Assistant
Phone
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Hepatitis B
and
Hepatitis D
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N202107067
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A Phase Ib, Open Label Study to Assess the Safety and Efficacy of Sequential Administration of P1101 and Anti-PD1 in Interferon-Naive Adults with Chronic Hepatitis B or D Infection
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Wei-Yu
Kao
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Gastroenterology
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Angel Chen
0909705050
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Endometriosis
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N202303035
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Clinical Validation of α1-Antitrypsin Isoforms as a Marker of Extrauterine Endometriosis
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Timothy Chiu
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Obstetrics
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Yin-Ju Chen
0227372181
#7606
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Heart failure
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N202305049
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HERMES: Effects of ziltivekimab versus placebo on morbidity and mortality in patients with heart failure with mildly reduced or preserved ejection fraction and systemic inflammation.
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Chun-Yao Huang
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Cardiology
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Yin-Ju Chen
0227372181
#7606
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Major adverse cardiovascular
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N202202023
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A randomized, double-blind, placebo-controlled multicenter study to evaluate the effect of inclisiran on preventing major adverse cardiovascular events in high-risk primary prevention patients (VICTORION-1 PREVENT)
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Chun-Yao Huang
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Cardiology
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Yin-Ju Chen
0227372181
#7606
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Skin disease
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N202305082
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Evaluation the supporting effect of microneedle patch for skin disease treatment
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Tsung-Ju
Lee
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Dermatology
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Ning-Xin Li
0968703924
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Hemodialysis
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N202207015
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An International, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Arrhythmia-Related Cardiovascular Outcomes in Participants on Chronic Hemodialysis with Recurrent Hyperkalemia (DIALIZE-Outcomes)
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Hsi-Hsien
Chen
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Nephrology
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Wan-Zhen Li
0975550912
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Hepatocellular carcinoma
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N202111033
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A Phase II Study to Evaluate the Efficacy and Safety of Activated T Lymphocytes (ATL) in Hepatocellular Carcinoma (HCC) Patients After Curative Treatment
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Wei-Yu
Kao
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Gastroenterology
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Yi-Ann Chen
0227372181
#7633
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Breast cancer
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N202011055
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SERENA-4: A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 (an Oral SERD) plus Palbociclib versus Anastrozole plus Palbociclib for the Treatment of Patients with Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease
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Jia-Ruey Tsai
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Hematology and Oncology
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Yi-Ann Chen
0227372181
#7633
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Breast cancer
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N202104119
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SERENA-6: A Phase III, Double-blind, Randomised Study to Assess Switching to AZD9833 (a Next Generation, Oral SERD) + CDK4/6 Inhibitor vs Continuing Aromatase Inhibitor (Letrozole or Anastrozole) + CDK4/6 Inhibitor in HR+/HER2- MBC Patients with Detectable ESR1 Mutation Without Disease Progression During 1L Treatment with Aromatase Inhibitor + CDK4/6 Inhibitor – A ctdna Guided Early Switch Study
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Jia-Ruey Tsai
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Hematology and Oncology
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Yi-Ann Chen
0227372181
#7633
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Urinary tract infections
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N202011055
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated Recurrent Urinary Tract Infections (rutis) in Women
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Ming-Che
Liu
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Urology
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Yin-Ju Chen
0227372181
#7606
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Obesity
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N202104119
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Efficacy and safety of semaglutide 2.4 mg once-weekly in adults with overweight and obesity (STEP 12)
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Wei Wang
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Colorectal Surgery
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Yin-Ju Chen
0227372181
#7606
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Obesity
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N202008042
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effect of Tirzepatide on the Reduction of Morbidity and Mortality in Adults with Obesity
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Chun-Yao Huang
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Cardiology
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Yin-Ju Chen
0227372181
#7606
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Lung cancer
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N202008042
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ON-TRK: prospective Non-interventional study in patients with locally advanced or metastatic TRK fusion cancer treated with larotrectinib
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Yen-Lin
Liu
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Pediatrics
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Ning-Xin Li
0968703924
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Lung cancer
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N202304153
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A Phase 3, Multicenter, Randomized, Double-Blind Study of MK- 7684 with Pembrolizumab as a Coformulation (MK-7684A) Versus Pembrolizumab Monotherapy as First Line Treatment for Participants With PD-L1 Positive Metastatic Non-Small Cell Lung Cancer
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Chao-Hua Chiu
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Pulmonary Medicine
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Wei-En
Zhang
0956195553
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Lung cancer
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N202211003
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A phase ii/iii multicenter study evaluating the efficacy and safety of multiple targeted therapies as treatments for patients with advanced or metastatic non-small cell lung cancer (nsclc) harboring actionable somatic mutations detected in blood (bfast: blood first assay screening trial)
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Chao-Hua Chiu
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Pulmonary Medicine
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Yin-Ju Chen
0227372181
#7606
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|
Lung cancer
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N202208040
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A Phase 1b, Multicenter, 2-Part, Open-Label Study of Datopotamab Deruxtecan (Dato-dxd) in Combination with Immunotherapy with or without Carboplatin in Participants with Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION‑Lung04)
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Chao-Hua Chiu
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Pulmonary Medicine
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Yi-Ting Lin
0960303216
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Lung cancer
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N202209096
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A Phase III, Two-Arm, Parallel, Randomized, Multi-Center, Open-Label, Global Study to Determine the Efficacy of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for First-Line Treatment of Patients with Metastatic Non-Small Cell Lung Cancer (mnsclc) (evolve-Lung02)
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Chao-Hua Chiu
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Pulmonary Medicine
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Yi-Ting Lin
0960303216
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Lung cancer
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N202303062
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A Phase 3, Randomized, Double-blind, Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mrna-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants With Resected Stage II, IIIA, IIIB (N2) Non-small Cell Lung Cancer
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Chao-Hua Chiu
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Pulmonary Medicine
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Yi-Ting Lin
0960303216
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Lung cancer
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N202011014
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A Phase 1 Multicenter Dose Escalation and Dose Expansion Study of Antibody-Drug Conjugate MYTX-011 in Subjects with Non-Small Cell Lung Cancer – kismet-01
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Chao-Hua Chiu
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Pulmonary Medicine
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Yin-Ju Chen
02-27372181
#7606
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Lung cancer
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N202012003
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A Phase III, Randomised, Controlled, Multi-centre, 3-Arm Study of Neoadjuvant Osimertinib as Monotherapy or in Combination with Chemotherapy versus Standard of Care Chemotherapy Alone for the Treatment of Patients with Epidermal Growth Factor Receptor Mutation Positive, Resectable Non-small Cell Lung Cancer (neoadaura)
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Han-Pin
Kuo
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Pulmonary Medicine
|
Xiao-Ling Liu
0926280226
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Lung cancer
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N202011014
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A Randomized, Placebo Controlled Study to Evaluate the Safety and Potential Efficacy of MS-20 In Combination With Pembrolizumab for the Treatment of Non-Small-Cell Lung Cancer
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Han-Pin
Kuo
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Pulmonary Medicine
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Ting-Ting Zeng
0975892927
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Non-alcoholic
fatty liver
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N202012003
|
Clinical Validation of Taking Bao-sang-li-qing in Adults with Non-Alcoholic Fatty Liver
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Ming-Che
Liu
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Urology
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Xiao-Ling Liu
0926280226
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Non-alcoholic
fatty liver
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N202104069
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Multi-center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of livphcd Capsules in the NAFLD Subjects
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Cheng Tiong
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Gastroenterology
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Yong-Ying
Zhang
0988128087
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Non-alcoholic
fatty liver
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N202110034
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The effect of semaglutide in subjects with non-cirrhotic non-alcoholic steatohepatitis
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Chun-Chao Chang
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Gastroenterology
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Wan-Zhen Li
0975550912
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Coronary syndrome
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N201801006
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A Phase 3, Randomized, Double-blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor xia Inhibitor, After a Recent Acute Coronary Syndrome
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Chun-Yao Huang
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Cardiology
|
Pei-Chuan Hsu
0227372181
#7635
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|
Influenza vaccine
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N201801006
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A Phase 3/3b, Randomized, Observer-blind, Multicenter Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an MF59-Adjuvanted Quadrivalent Subunit Inactivated Influenza Vaccine Compared to a Quadrivalent Influenza Vaccine in Adults ≥65 Years of Age
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Ming-Che
Liu
|
Urology
|
Pei-Chuan Hsu
0227372181
#7635
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|
Systemic lupus erythematosus
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N202205076
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A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Nipocalimab in Adult Participants with Active Systemic Lupus Erythematosus
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Chi-Ching Chang
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Rheumatology
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Ning-Xin Li
0968703924
|
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Esophageal tissue
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N202205032
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Autologous mucosal cell products for repairing defects in the esophagus:process validation for use in clinical research
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Chia-Yu
Wu
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Oral Surgery
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Shu-Min Chen
0983670782
|
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Sj?gren's syndrome
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N202205037
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A randomized, double-blind, placebo controlled, 3-arm multicenter phase 3 study to assess the efficacy and safety of ianalumab in patients with active Sjögren’s syndrome (NEPTUNUS-2)
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Chi-Ching Chang
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Rheumatology
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Ting-Ting Zeng
0975892927
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Asthma
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N202207024
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A Randomized, Single-dose, Double-blind, Double-dummy, Placebo and Active Controlled, Crossover Design Study Using Bronchoprovocation to Evaluate the Pharmacodynamic Equivalence of the Test and Reference Metered Dose Inhalers (mdis) Containing Albuterol Sulfate in Adult Patients with Stable Mild Asthma
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Pai-Chien Chou
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Pulmonary Medicine/Sleep Clinic
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Ting-Ting Zeng
0975892927
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|
Asthma
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N202107026
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A randomized, double-blind, placebo controlled study assessing the long-term effect of dupilumab on prevention of lung function decline in patients with uncontrolled moderate to severe asthma
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Pai-Chien Chou
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Pulmonary Medicine/Sleep Clinic
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Yin-Ju Chen
0227372181
#7606
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|
Asthma
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N202107026
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A Randomized, Double-Blind, Double Dummy, Parallel Group, Multicenter 24 to 52 Week Variable Length Study to Assess the Efficacy and Safety of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler (MDI) Relative to Budesonide and Formoterol Fumarate MDI and Symbicort® Pressurized MDI in Adult and Adolescent Participants with Inadequately Controlled Asthma (KALOS)
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Pai-Chien Chou
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Pulmonary Medicine/Sleep Clinic
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Yin-Ju Chen
0227372181
#7606
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Asthma
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N202202050
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A Randomized, Placebo controlled, Double blind Phase iia Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of Multiple Intravenous Doses of FB704A in Adults with Severe Asthma
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Han-Pin
Kuo
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Pulmonary Medicine
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Yi-Ann Chen
0227372181
#7633
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|
Pancreatic cancer
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N202207029
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A Prospective, Non-interventional, Multi-center Study to Evaluate the Clinical Validity of E.V.A. Select in Patients with Pancreatic Ductal Adenocarcinoma
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Long-Sheng Lu
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Radiation Oncology
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Yin-Ju Chen
0227372181
#7606
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|
Spinal cord injuries
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N202112066
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A randomized double-blind, placebo-controlled, multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease (VICTORION-2 PREVENT)
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Chun-Yao Huang
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Cardiology
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Yin-Ju Chen
0227372181
#7606
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Spinal cord injuries
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N202111011
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A Randomized Controlled Phase II, Two-Arm Study of Umbilical Cord Blood Cell Trans-plant (MC001) into Injured Spinal Cord followed by the Locomotor Training for Patients with Chronic Spinal Cord Injuries (SCI).
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Yung-Hsiao
Chiang
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Neurosurgery
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Wei-Ling Lan
0970405675
|
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Hypertension
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N202207020
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A Multicentre, Randomized, Doubleblind Study to Evaluate and Compare the Efficacy and Safety of 8- week Treatment with Azilsartan Medoxomil and Amlodipine Besylate Combined and Alone in Mild-to-moderate Essential Hypertensive Subjects
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Chun-Yao Huang
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Cardiology
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Jia-Hua Xie
0968703924
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|
Hypertension
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N202209050
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Clinical evaluation on accuracy of HL158 series Blood Pressure Monitor
|
Ming-Che Liu
|
Urology
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Yin-Ju Chen
0227372181
#7606
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|
Hypertension
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N202211058
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A multi-center, randomized, double-blind, parallel-group, 20-week dose-finding study to evaluate efficacy, safety, and tolerability of XXB750 in patients with resistant hypertension
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Chun-Yao Huang
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Cardiology
|
Pi-Wen Hsu
0987610280
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Hypertension
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N201701024
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A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy and Safety of Baxdrostat in Participants with Uncontrolled Hypertension on Two or More Medications including Participants with Resistant Hypertension
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Chun-Yao Huang
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Cardiology
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Feng-Yi Chou
0227372181
#7602
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|
Hypertension
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N201701024
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A Phase III, Randomised, Double -Blind, Active-controlled Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination with Dapagliflozin Compared with Dapagliflozin Alone on Chronic Kidney Disease (CKD) Progression in Participants with CKD and High Blood Pressure
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Chun-Yao Huang
|
Cardiology
|
Feng-Yi Chou
0227372181
#7602
|
|
Hypercholesterolemia
|
N202005098
|
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-0616 in Adults With Hypercholesterolemia
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Chun-Yao Huang
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Cardiology
|
Feng-Yi Chou
0227372181
#7602
|
|
Healthy volunteer
|
N202005098
|
A Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Healthy Volunteers and Patients with Hemophilia A
|
Chia-Yau Chang
|
Pediatrics
|
Feng-Yi Chou
0227372181
#7602
|
|
Healthy volunteer
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N202301007
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Human Blank Matrix Collection in Healthy Volunteers under Fasting Conditions Used in Method Development, Validation and Sample Analysis
|
Ming-Che
Liu
|
Urology
|
Ting-Ting Zeng
0975892927
|
|
Cell therapy
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N202211052
|
Development of Autologous Adipose-Derived Mesenchymal Stem Cell Culture Procedure
|
Li-Wei
Tang
|
Plastic Surgery
|
Chen-Chun Chu
0933085872
|
|
Cell therapy
|
N202303029
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Cell function test and cell process validation of autoimmune cell products
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Ming-Che
Liu
|
Urology
|
Chen-Chun Chu
0933085872
|
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Solid tumors
|
N202203154
|
A Phase 1 first in human study evaluating safety, pharmacokinetics and efficacy of ABBV-400 in adult subjects with advanced solid tumors
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Pai-Chien Chou
|
Pulmonary Medicine/Sleep Clinic
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Pei-Rong Luo
0911135352
|
|
Solid tumors
|
N202212020
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Master screening study to determine biomarker status and potential trial eligibility for patients with malignant tumors
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Chao-Hua Chiu
|
Pulmonary Medicine
|
Jia-Hua Xie
0968703924
|
|
Solid tumors
|
N202011053
|
A First-in-Human, Open-label, Dose-escalation Trial with Expansion Cohorts to Evaluate Safety and Anti-Tumor Activity of GEN1042 in Subjects With Malignant Solid Tumors
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Chao-Hua Chiu
|
Pulmonary Medicine
|
Yin-Ju Chen
0227372181
#7606
|
|
Solid tumors
|
N202011053
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A Phase I, Open-label, Dose-finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TRX-920 Oral Gel (10 mg and 30 mg) in Patients with Advanced Solid Tumors
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Chao-Hua Chiu
|
Pulmonary Medicine
|
Yin-Ju Chen
0227372181
#7606
|
|
Solid tumors
|
N202106078
|
A Phase 3 Open-Label, Randomized, Controlled, Global Study of Telisotuzumab Vedotin (ABBV-399) Versus Docetaxel in Subjects with Previously Treated c-Met Overexpressing, EGFR Wildtype, Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer
|
Shih-Hsin Hsiao
|
Pulmonary Medicine
|
Ying-Zhen Li
0916700055
|
|
Gout
|
N202106078
|
A multi-center, randomized, double-blind, active-controlled, therapeutic confirmatory, phase III study to compare and evaluate the efficacy and safety of Epaminurad with Febuxostat in gout patients
|
Chi-Ching Chang
|
Rheumatology
|
Feng-Yi Chou
0227372181
#7602
|
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Interstitial lung disease
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N202206054
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Non-Interventional Collecting Evidences For ILD in Taiwan:Optimized Novel Therapy
|
Chi-Li
Chung
|
Pulmonary Medicine
|
Hsiang-Yun Huang
0987841201
|
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Covid
|
N202104069
|
The clinical verification plan of GB COVID-19 Ag Saliva for home-using
|
Ming-Che
Liu
|
Urology
|
Yong-Ying Zhang
0988128087
|
|
Covid
|
N202107117
|
The clinical verification plan of GB COVID-19 Ag POCT for home-using
|
Shy-Shin Chang
|
Family Medicine
|
Ning-Xin Li
0968703924
|
|
Chronic obstructive pulmonary disease
|
N202208038
|
Randomized, double-blind, placebo-controlled, parallelgroup Phase 3 study to evaluate the efficacy, safety, and tolerability of SAR440340/REGN3500/Itepekimab (anti-IL-33 mab) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD)
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Pai-Chien Chou
|
Pulmonary Medicine/Sleep Clinic
|
Yin-Ju Chen
0227372181
#7606
|
|
Chronic obstructive pulmonary disease
|
N202101003
|
A phase iii, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of astegolimab in patients with chronic obstructive pulmonary disease
|
Pai-Chien Chou
|
Pulmonary Medicine/Sleep Clinic
|
Yin-Ju Chen
0227372181
#7606
|
|
Chronic kidney disease
|
N202101003
|
A Phase 3, International, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants with CKD and Hyperkalaemia or at Risk of Hyperkalaemia
|
Hsi-Hsien
Chen
|
Nephrology
|
Yin-Ju Chen
0227372181
#7606
|
|
Kidney disease
|
N202303052
|
A Phase III, Randomised, Multicentre, Double-blind Study to Evaluate the Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin Alone in Participants with Chronic Kidney Disease and High Proteinuria
|
Hsi-Hsien
Chen
|
Nephrology
|
Wei-Ling Lan
0970405675
|
|
Rhinosinusitis
|
N202207026
|
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Benralizumab in Patients with Eosinophilic Chronic Rhinosinusitis with Nasal Polyps (ORCHID)
|
Pai-Chien Chou
|
Pulmonary Medicine/Sleep Clinic
|
Yin-Ju Chen
0227372181
#7606
|
|
Knee osteoarthritis
|
N202011029
|
A Phase I, Open-Label, Dose Escalation Study to Evaluate the Safety and Tolerability after Intra-Articular (IA) Injection of UMC119-06-05 in adult subjects with Mild to Moderate Knee Osteoarthritis (KOA)
|
Jia-Lin
Wu
|
Orthopedics
|
Pei-Chuan Hsu
0227372181
#7635
|
|
Diabetes
|
N202201007
|
Efficacy and safety of co-administered cagrilintide and semaglutide (cagrisema) s.c. In doses 2.4/2.4 mg and 1.0/1.0 mg once weekly versus semaglutide 2.4 mg and 1.0 mg, cagrilintide 2.4 mg and placebo in participants with type 2 diabetes inadequately controlled on metformin with or without an SGLT2 inhibitor
|
Shuen-Fu Weng
|
Endocrinology and Metabolism
|
Pei-Chuan Hsu
0227372181
#7635
|
|
Cancer patients
|
N202011029
|
A Prospective Observational Human Subject Research to Explore the HLA-A*02:01 Allele Frequency and the NY-ESO-1 Expression Status in Cancer Patients in Taiwan
|
Shih-Hsin Hsiao
|
Pulmonary Medicine
|
Pei-Chuan Hsu
0227372181
#7635
|